Matcha green tea inhibits the propagation of breast cancer stem cells ....
Research Paper - Published: August 23, 2018
Biomedical research indicates that Matcha Green Tea (MGT) is indeed sufficient to inhibit the propagation of breast Cancer Stem Cells (CSCs), with an IC-50 of ~0.2 mg/ml, in tissue culture. This is consistent with the idea that MGT may have significant therapeutic potential, by mediating the metabolic reprogramming of cancer cells.
Interestingly, several recent studies have suggested that Japanese green tea has anti-proliferative, anti-oxidant, anti-bacterial, and chemo-preventive effects. In direct support of this notion, it has been demonstrated that a key component of green tea, namely epigallocatechin-3-gallate, behaves as an anti-oxidant and shows anti-tumor effects against breast cancer cells.
Recently, the therapeutic effects of green tea catechins on breast tumorigenesis were evaluated using pre-clinical models, as well as clinical trials. It was demonstrated that tea has other protective effects, such as reducing the risk of mortality from heart disease and stroke (cerebrovascular accident). Furthermore, a meta-analysis of epidemiological studies in 2006 suggested that green tea may lower the risk of developing colorectal cancer.
Green tea may also interact with other components of the diet, including those natural products contained within soy and mushrooms. Consumption of green tea could partially explain why Asian-American women show a decreased risk for developing breast cancer.
A subsequent study, using green tea supplements, supports the idea that green tea extracts could be used in the chemo-prevention of metachronous colorectal adenomas. Finally, green tea has shown positive benefits in reducing Acute Myeloid Leukaemia (AML) risk and prostate cancer. Taken together, these studies suggest that green tea or its components, may be very useful as anti-cancer agents.
The full article can be accessed here.